Rice-based oral antibody fragment prophylaxis and therapy against rotavirus infection

Rotavirus-induced diarrhea is a life-threatening disease in immunocompromised individuals and in children in developing countries. We have developed a system for prophylaxis and therapy against rotavirus disease using transgenic rice expressing the neutralizing variable domain of a rotavirus-specifi...

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Detalhes bibliográficos
Main Authors: Tokuhara, Daisuke, ρlvarez, Beatriz, Mejima, Mio, Hiroiwa, Tomoko, Takahashi, Yuko, Kurokawa, Shiho, Kuroda, Masaharu, Oyama, Masaaki, Kozuka-Hata, Hiroko, Nochi, Tomonori, Sagara, Hiroshi, Aladin, Farah, Marcotte, Harold, Frenken, Leon G.J., Iturriza-Gómara, Miren, Kiyono, Hiroshi, Hammarström, Lennart, Yuki, Yoshikazu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754275/
https://ncbi.nlm.nih.gov/pubmed/23925294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70266
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