Prolactin promotes cartilage survival and attenuates inflammation in inflammatory arthritis

Chondrocytes are the only cells in cartilage, and their death by apoptosis contributes to cartilage loss in inflammatory joint diseases, such as rheumatoid arthritis (RA). A putative therapeutic intervention for RA is the inhibition of apoptosis-mediated cartilage degradation. The hormone prolactin...

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Detalhes bibliográficos
Main Authors: Adán, Norma, Guzmán-Morales, Jessica, Ledesma-Colunga, Maria G., Perales-Canales, Sonia I., Quintanar-Stéphano, Andrés, López-Barrera, Fernando, Méndez, Isabel, Moreno-Carranza, Bibiana, Triebel, Jakob, Binart, Nadine, Martínez de la Escalera, Gonzalo, Thebault, Stéphanie, Clapp, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754268/
https://ncbi.nlm.nih.gov/pubmed/23908112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69485
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