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Olfm4 deletion enhances defense against Staphylococcus aureus in chronic granulomatous disease

Chronic granulomatous disease (CGD) patients have recurrent life-threatening bacterial and fungal infections. Olfactomedin 4 (OLFM4) is a neutrophil granule protein that negatively regulates host defense against bacterial infection. The goal of this study was to evaluate the impact of Olfm4 deletion...

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Detalhes bibliográficos
Main Authors: Liu, Wenli, Yan, Ming, Sugui, Janyce A., Li, Hongzhen, Xu, Chengfu, Joo, Jungsoo, Kwon-Chung, Kyung J., Coleman, William G., Rodgers, Griffin P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754258/
https://ncbi.nlm.nih.gov/pubmed/23908114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI68453
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