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Potential applications for biguanides in oncology
Metformin is widely prescribed for the treatment of type II diabetes. Recently, it has been proposed that this compound or related biguanides may have antineoplastic activity. Biguanides may exploit specific metabolic vulnerabilities of transformed cells by acting on them directly, or may act by ind...
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3754250/ https://ncbi.nlm.nih.gov/pubmed/23999444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67232 |
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