Mobilizing monocytes to cross-present circulating viral antigen in chronic infection

Selection of antigens for therapeutic vaccination against chronic viral infections is complicated by pathogen genetic variations. We tested whether antigens present during persistent viral infections could provide a personalized antigenic reservoir for therapeutic T cell expansion in humans. We focu...

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Autors principals: Gehring, Adam J., Haniffa, Muzlifah, Kennedy, Patrick T., Ho, Zi Zong, Boni, Carolina, Shin, Amanda, Banu, Nasirah, Chia, Adeline, Lim, Seng Gee, Ferrari, Carlo, Ginhoux, Florent, Bertoletti, Antonio
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754243/
https://ncbi.nlm.nih.gov/pubmed/23908113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66043
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