The Trypanosoma brucei gambiense Secretome Impairs Lipopolysaccharide-Induced Maturation, Cytokine Production, and Allostimulatory Capacity of Dendritic Cells

Trypanosoma brucei gambiense, a parasitic protozoan belonging to kinetoplastids, is the main etiological agent of human African trypanosomiasis (HAT), or sleeping sickness. One major characteristic of this disease is the dysregulation of the host immune system. The present study demonstrates that th...

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Main Authors: Garzón, Edwin, Holzmuller, Philippe, Bras-Gonçalves, Rachel, Vincendeau, Philippe, Cuny, Gérard, Lemesre, Jean Loup, Geiger, Anne
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Fungal and Parasitic Infections
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754197/
https://ncbi.nlm.nih.gov/pubmed/23798533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00125-13
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