UPF1 Is Crucial for the Infectivity of Human Immunodeficiency Virus Type 1 Progeny Virions

The SF1 helicase MOV10 is an antiviral factor that is incorporated into human immunodeficiency virus type 1 (HIV-1) virions. We now report that HIV-1 virions also incorporate UPF1, which belongs to the same SF1 helicase subfamily as MOV10 and functions in the nonsense-mediated decay (NMD) pathway. U...

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Bibliographic Details
Main Authors: Serquiña, Anna Kristina P., Das, Suman R., Popova, Elena, Ojelabi, Ogooluwa A., Roy, Christian K., Göttlinger, Heinrich G.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754033/
https://ncbi.nlm.nih.gov/pubmed/23785196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00925-13
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