An Inactivated Cell Culture Japanese Encephalitis Vaccine (JE-ADVAX) Formulated with Delta Inulin Adjuvant Provides Robust Heterologous Protection against West Nile Encephalitis via Cross-Protective Memory B Cells and Neutralizing Antibody

West Nile virus (WNV), currently the cause of a serious U.S. epidemic, is a mosquito-borne flavivirus and member of the Japanese encephalitis (JE) serocomplex. There is currently no approved human WNV vaccine, and treatment options remain limited, resulting in significant mortality and morbidity fro...

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Hlavní autoři: Petrovsky, Nikolai, Larena, Maximilian, Siddharthan, Venkatraman, Prow, Natalie A., Hall, Roy A., Lobigs, Mario, Morrey, John
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754008/
https://ncbi.nlm.nih.gov/pubmed/23864620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00480-13
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