Dissection of the C-Terminal Region of E1A Redefines the Roles of CtBP and Other Cellular Targets in Oncogenic Transformation

Human adenovirus E1A makes extensive connections with the cellular protein interaction network. By doing so, E1A can manipulate many cellular programs, including cell cycle progression. Through these reprogramming events, E1A functions as a growth-promoting oncogene and has been used extensively to...

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Detalhes bibliográficos
Main Authors: Cohen, M. J., Yousef, A. F., Massimi, P., Fonseca, G. J., Todorovic, B., Pelka, P., Turnell, A. S., Banks, L., Mymryk, J. S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Transformation and Oncogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753994/
https://ncbi.nlm.nih.gov/pubmed/23864635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00786-13
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