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Conservation of structure and mechanism by Trm5 enzymes

Enzymes of the Trm5 family catalyze methyl transfer from S-adenosyl methionine (AdoMet) to the N(1) of G37 to synthesize m(1)G37-tRNA as a critical determinant to prevent ribosome frameshift errors. Trm5 is specific to eukaryotes and archaea, and it is unrelated in evolution from the bacterial count...

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Detalhes bibliográficos
Main Authors: Christian, Thomas, Gamper, Howard, Hou, Ya-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753926/
https://ncbi.nlm.nih.gov/pubmed/23887145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.039503.113
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