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Computational detection of abundant long-range nucleotide covariation in Drosophila genomes

Functionally important nucleotide base-pairing often manifests itself in sequence alignments in the form of compensatory base changes (covariation). We developed a novel index-based computational method (CovaRNA) to detect long-range covariation on a genomic scale, as well as another computational m...

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Détails bibliographiques
Auteurs principaux: Bindewald, Eckart, Shapiro, Bruce A.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753924/
https://ncbi.nlm.nih.gov/pubmed/23887147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.037630.112
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