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Sites of Acetylation on Newly Synthesized Histone H4 Are Required for Chromatin Assembly and DNA Damage Response Signaling

The best-characterized acetylation of newly synthesized histone H4 is the diacetylation of the NH(2)-terminal tail on lysines 5 and 12. Despite its evolutionary conservation, this pattern of modification has not been shown to be essential for either viability or chromatin assembly in any model organ...

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Detalhes bibliográficos
Main Authors: Ge, Zhongqi, Nair, Devi, Guan, Xiaoyan, Rastogi, Neha, Freitas, Michael A., Parthun, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753916/
https://ncbi.nlm.nih.gov/pubmed/23775118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00460-13
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