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Sites of Acetylation on Newly Synthesized Histone H4 Are Required for Chromatin Assembly and DNA Damage Response Signaling
The best-characterized acetylation of newly synthesized histone H4 is the diacetylation of the NH(2)-terminal tail on lysines 5 and 12. Despite its evolutionary conservation, this pattern of modification has not been shown to be essential for either viability or chromatin assembly in any model organ...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753916/ https://ncbi.nlm.nih.gov/pubmed/23775118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00460-13 |
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