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CD81 Controls Sustained T Cell Activation Signaling and Defines the Maturation Stages of Cognate Immunological Synapses

In this study, we investigated the dynamics of the molecular interactions of tetraspanin CD81 in T lymphocytes, and we show that CD81 controls the organization of the immune synapse (IS) and T cell activation. Using quantitative microscopy, including fluorescence recovery after photobleaching (FRAP)...

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Detalhes bibliográficos
Main Authors: Rocha-Perugini, V., Zamai, M., González-Granado, J. M., Barreiro, O., Tejera, E., Yañez-Mó, M., Caiolfa, V. R., Sanchez-Madrid, F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753866/
https://ncbi.nlm.nih.gov/pubmed/23858057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00302-13
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