Phase I Trial of (90)Y-DOTA(0)-Tyr(3)-Octreotide Therapy in Children and Young Adults with Refractory Solid Tumors That Express Somatostatin Receptors

PURPOSE: Conduct a Phase I trial of (90)Y-DOTA(0)-Tyr(3)-octreotide to determine the dose/toxicity profile in children and young adults with somatostatin receptor positive tumors. METHODS: A 3×3 design was utilized to determine the highest tolerable dose of (90)Y-DOTA(0)-Tyr(3)-octreotide with admin...

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Autori principali: Menda, Yusuf, Sue O’Dorisio, M., Kao, Simon, Khanna, Geetika, Michael, Stacy, Connolly, Mary, Babich, John, O’Dorisio, Thomas, Bushnell, David, Madsen, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753801/
https://ncbi.nlm.nih.gov/pubmed/20847174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.110.075226
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