Regression Modeling and Meta-Analysis of Diagnostic Accuracy of SNP-Based Pathogenicity Detection Tools for UGT1A1 Gene Mutation

Aims. This review summarized all available evidence on the accuracy of SNP-based pathogenicity detection tools and introduced regression model based on functional scores, mutation score, and genomic variation degree. Materials and Methods. A comprehensive search was performed to find all mutations r...

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Autori principali: Rahim, Fakher, Galehdari, Hamid, Mohammadi-asl, Javad, Saki, Najmaldin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753762/
https://ncbi.nlm.nih.gov/pubmed/23997956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/546909
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