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Regulation of osteoclasts by membrane-derived lipid mediators
Osteoclasts are bone-resorbing cells of monocytic origin. An imbalance between bone formation and resorption can lead to osteoporosis or osteopetrosis. Osteoclastogenesis is triggered by RANKL- and IP3-induced Ca(2+) influx followed by activation of NFATc1, a master transcription factor for osteocla...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Basel
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753467/ https://ncbi.nlm.nih.gov/pubmed/23296124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-1238-4 |
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