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Epigenetic control of Epstein–Barr virus transcription – relevance to viral life cycle?

DNA methylation normally leads to silencing of gene expression but Epstein–Barr virus (EBV) provides an exception to the epigenetic paradigm. DNA methylation is absolutely required for the expression of many viral genes. Although the viral genome is initially un-methylated in newly infected cells, i...

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Detalhes bibliográficos
Autor principal: Sinclair, Alison J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753449/
https://ncbi.nlm.nih.gov/pubmed/23986773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00161
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