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Alternative mRNA Splicing from the Glial Fibrillary Acidic Protein (GFAP) Gene Generates Isoforms with Distinct Subcellular mRNA Localization Patterns in Astrocytes

The intermediate filament network of astrocytes includes Glial fibrillary acidic protein (Gfap) as a major component. Gfap mRNA is alternatively spliced resulting in generation of different protein isoforms where Gfapα is the most predominant isoform. The Gfapδ isoform is expressed in proliferating...

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Bibliografische gegevens
Hoofdauteurs: Thomsen, Rune, Daugaard, Tina F., Holm, Ida E., Nielsen, Anders Lade
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753360/
https://ncbi.nlm.nih.gov/pubmed/23991052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072110
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