Alternative mRNA Splicing from the Glial Fibrillary Acidic Protein (GFAP) Gene Generates Isoforms with Distinct Subcellular mRNA Localization Patterns in Astrocytes

The intermediate filament network of astrocytes includes Glial fibrillary acidic protein (Gfap) as a major component. Gfap mRNA is alternatively spliced resulting in generation of different protein isoforms where Gfapα is the most predominant isoform. The Gfapδ isoform is expressed in proliferating...

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Main Authors: Thomsen, Rune, Daugaard, Tina F., Holm, Ida E., Nielsen, Anders Lade
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753360/
https://ncbi.nlm.nih.gov/pubmed/23991052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072110
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