Generation of a Mouse Model with Down-Regulated U50 snoRNA (SNORD50) Expression and Its Organ-Specific Phenotypic Modulation

Box C/D-type small nucleolar RNAs (snoRNAs) are functional RNAs responsible for mediating 2′-O-ribose methylation of ribosomal RNAs (rRNAs) within the nucleolus. In the past years, evidence for the involvement of human U50 snoRNA in tumorigenesis has been accumulating. We previously identified U50HG...

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Main Authors: Soeno, Yuuichi, Fujita, Kazuya, Kudo, Tomoo, Asagiri, Masataka, Kakuta, Shigeru, Taya, Yuji, Shimazu, Yoshihito, Sato, Kaori, Tanaka-Fujita, Ritsuko, Kubo, Sachiko, Iwakura, Yoichiro, Nakamura, Yoshikazu, Mori, Shigeo, Aoba, Takaaki
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753356/
https://ncbi.nlm.nih.gov/pubmed/23991050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072105
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