The Candida albicans Lanosterol 14-α-Demethylase (ERG11) Gene Promoter Is Maximally Induced after Prolonged Growth with Antifungal Drugs

The azole antifungal drugs that target lanosterol 14-α-demethylase, encoded by the ERG11 gene, are used to treat a variety of infections caused by Candida albicans. Azoles are known to induce expression of ERG11 mRNA. The ERG11 promoter was cloned 5′ of the luciferase-coding region, and the inductio...

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Detalhes bibliográficos
Main Authors: Song, Jia L., Beth Harry, Jo, Eastman, Richard T., Oliver, Brian G., White, Theodore C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC375326/
https://ncbi.nlm.nih.gov/pubmed/15047513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.4.1136-1144.2004
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