Pathogenic Intestinal Bacteria Enhance Prostate Cancer Development via Systemic Activation of Immune Cells in Mice

A role for microbes has been suspected in prostate cancer but difficult to confirm in human patients. We show here that a gastrointestinal (GI) tract bacterial infection is sufficient to enhance prostate intraepithelial neoplasia (PIN) and microinvasive carcinoma in a mouse model. We found that anim...

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Main Authors: Poutahidis, Theofilos, Cappelle, Kelsey, Levkovich, Tatiana, Lee, Chung-Wei, Doulberis, Michael, Ge, Zhongming, Fox, James G., Horwitz, Bruce H., Erdman, Susan E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753256/
https://ncbi.nlm.nih.gov/pubmed/23991210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073933
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