Determination of Paclitaxel Distribution in Solid Tumors by Nano-Particle Assisted Laser Desorption Ionization Mass Spectrometry Imaging

A sensitive, simple and reproducible protocol for nanoparticle-assisted laser desorption/ionization mass spectrometry imaging technique is described. The use of commercially available TiO(2) nanoparticles abolishes heterogeneous crystallization, matrix background interferences and enhances signal de...

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Autors principals: Morosi, Lavinia, Spinelli, Pietro, Zucchetti, Massimo, Pretto, Francesca, Carrà, Andrea, D’Incalci, Maurizio, Giavazzi, Raffaella, Davoli, Enrico
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753243/
https://ncbi.nlm.nih.gov/pubmed/23991120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072532
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