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Role of Fecal Clostridium difficile Load in Discrepancies Between Toxin Tests and PCR: Is Quantitation the Next Step in C. difficile Testing?

PURPOSE: Direct tests for Clostridium difficile are 30–50% more sensitive than tests for C. difficile toxins but the reasons for this discrepancy are incompletely understood. In addition to toxin degradation and strain differences, we hypothesized that C. difficile concentration could be important i...

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Detalhes bibliográficos
Main Authors: Leslie, Jhansi L., Cohen, Stuart H., Solnick, Jay V., Polage, Christopher R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753214/
https://ncbi.nlm.nih.gov/pubmed/22814877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10096-012-1695-6
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