NCX-1000, a NO-releasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertension

Portal hypertension resulting from increased intrahepatic resistance is a common complication of chronic liver diseases and a leading cause of death in patients with liver cirrhosis, a scarring process of the liver that includes components of both increased fibrogenesis and wound contraction. A redu...

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Bibliographische Detailangaben
Hauptverfasser: Fiorucci, Stefano, Antonelli, Elisabetta, Morelli, Olivia, Mencarelli, Andrea, Casini, Alessandro, Mello, Tommaso, Palazzetti, Barbara, Tallet, Dominique, del Soldato, Piero, Morelli, Antonio
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2001
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC37532/
https://ncbi.nlm.nih.gov/pubmed/11447266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151136298
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