Mutations in a 23S rRNA Gene of Chlamydia trachomatis Associated with Resistance to Macrolides

For six clinical isolates of Chlamydia trachomatis, in vitro susceptibility to erythromycin, azithromycin, and josamycin has been determined. Four isolates were resistant to all the antibiotics and had the mutations A2058C and T2611C (Escherichia coli numbering) in the 23S rRNA gene. All the isolate...

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Hlavní autoři: Misyurina, O. Y., Chipitsyna, E. V., Finashutina, Y. P., Lazarev, V. N., Akopian, T. A., Savicheva, A. M., Govorun, V. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC375314/
https://ncbi.nlm.nih.gov/pubmed/15047540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.4.1347-1349.2004
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