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Improving Peptide Identification Sensitivity in Shotgun Proteomics by Stratification of Search Space

Due to its high specificity, trypsin is the enzyme of choice in shotgun proteomics. Nonetheless, several publications do report the identification of semi-tryptic and non-tryptic peptides. Many of these peptides are conjectured to be signaling peptides or to have formed during sample preparation. It...

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Autores principales: Alves, Gelio, Yu, Yi-Kuo
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753091/
https://ncbi.nlm.nih.gov/pubmed/23668635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr301139y
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