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Improving Peptide Identification Sensitivity in Shotgun Proteomics by Stratification of Search Space
Due to its high specificity, trypsin is the enzyme of choice in shotgun proteomics. Nonetheless, several publications do report the identification of semi-tryptic and non-tryptic peptides. Many of these peptides are conjectured to be signaling peptides or to have formed during sample preparation. It...
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2013
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753091/ https://ncbi.nlm.nih.gov/pubmed/23668635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr301139y |
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