Functional defect of peripheral neutrophils in mice with induced deletion of CXCR2

Type 2 CXC chemokine receptor CXCR2 plays roles in development, tumorigenesis and inflammation. CXCR2 also promotes demyelination and decreases remyelination by actions toward hematopoietic cells and non-hematopoietic cells. Germline CXCR2 deficient (Cxcr2(−/−)) mice reported in 1994 revealed the co...

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Main Authors: Liu, LiPing, Li, MeiZhang, Spangler, Lisa C., Spear, Charles, Veenstra, Mike, Darnall, Lindsey, Chang, Cathleen, Cotleur, Anne C., Ransohoff, Richard M.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753089/
https://ncbi.nlm.nih.gov/pubmed/23650205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22401
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