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Enhancement of Autophagy by Simvastatin through Inhibition of Rac1-mTOR Signaling Pathway in Coronary Arterial Myocytes

BACKGROUND/AIMS: In addition to their action of lowering blood cholesterol levels, statins modulate biological characteristics and functions of arterial myocytes such as viability, proliferation, apoptosis, survival and contraction. The present study tested whether simvastatin, as a prototype statin...

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Bibliografski detalji
Glavni autori: Wei, Yu-Miao, Li, Xiang, Xu, Ming, Abais, Justine M., Chen, Yang, Riebling, Christopher R., Boini, Krishna M., Li, Pin-Lan, Zhang, Yang
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753088/
https://ncbi.nlm.nih.gov/pubmed/23817226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000350111
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