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Depletion and dysfunction of Vγ2Vδ2 T cells in HIV disease: mechanisms, impacts and therapeutic implications

Infection with human immunodeficiency virus (HIV) disrupts the balance among γδ T cell subsets, with increasing Vδ1+ cells and substantial depletion of circulating Vδ2+ cells. Depletion is an indirect effect of HIV in CD4-negative Vδ2 cells, but is specific for phosphoantigen-responsive subpopulatio...

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書誌詳細
主要な著者: Li, Haishan, Chaudry, Suchita, Poonia, Bhawna, Shao, Yiming, Pauza, C David
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753036/
https://ncbi.nlm.nih.gov/pubmed/23241900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2012.50
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