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Molecular interplay between cdk4 and p21 dictates G(0)/G(1) cell cycle arrest in prostate cancer cells

This study examined the effect of 3, 9-dihydroxy-2-prenylcoumestan (pso), a furanocoumarin, on PC-3 and C4-2B castration-resistant prostate cancer (CRPC) cell lines. Pso caused significant G(0)/G(1) cell cycle arrest and inhibition of cell growth. Molecular analysis of cyclin (D1, D2, D3, and E), cy...

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Bibliografische gegevens
Hoofdauteurs: Gulappa, Thippeswamy, Reddy, Ramadevi Subramani, Suman, Suman, Nyakeriga, Alice M., Damodaran, Chendil
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752915/
https://ncbi.nlm.nih.gov/pubmed/23684928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.05.014
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