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Molecular interplay between cdk4 and p21 dictates G(0)/G(1) cell cycle arrest in prostate cancer cells
This study examined the effect of 3, 9-dihydroxy-2-prenylcoumestan (pso), a furanocoumarin, on PC-3 and C4-2B castration-resistant prostate cancer (CRPC) cell lines. Pso caused significant G(0)/G(1) cell cycle arrest and inhibition of cell growth. Molecular analysis of cyclin (D1, D2, D3, and E), cy...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3752915/ https://ncbi.nlm.nih.gov/pubmed/23684928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.05.014 |
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