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Synthetic HLA-G proteins for therapeutic use in transplantation

The human leukocyte antigen (HLA)-G is a tolerogenic molecule, whose expression by allografts is associated with better acceptance. An increasing interest in producing HLA-G as a clinical-grade molecule for therapy use is impaired by its complexity and limited stability. Our purpose was to engineer...

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Bibliographic Details
Main Authors: LeMaoult, Joel, Daouya, Marina, Wu, Juan, Loustau, Maria, Horuzsko, Anatolij, Carosella, Edgardo D.
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752534/
https://ncbi.nlm.nih.gov/pubmed/23752205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-228247
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