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Synthetic HLA-G proteins for therapeutic use in transplantation

The human leukocyte antigen (HLA)-G is a tolerogenic molecule, whose expression by allografts is associated with better acceptance. An increasing interest in producing HLA-G as a clinical-grade molecule for therapy use is impaired by its complexity and limited stability. Our purpose was to engineer...

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Main Authors: LeMaoult, Joel, Daouya, Marina, Wu, Juan, Loustau, Maria, Horuzsko, Anatolij, Carosella, Edgardo D.
格式: Artigo
語言:Inglês
出版: Federation of American Societies for Experimental Biology 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752534/
https://ncbi.nlm.nih.gov/pubmed/23752205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-228247
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