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Role of Topoisomerase Mutations and Efflux in Fluoroquinolone Resistance of Bacteroides fragilis Clinical Isolates and Laboratory Mutants

Twelve laboratory mutants and 32 ciprofloxacin-resistant isolates of Bacteroides fragilis were examined for the mechanism(s) of fluoroquinolone resistance. Five mutants had mutations in gyrA. One mutant and two clinical isolates contained a mutation in gyrB. Eight mutants and five clinical isolates...

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Autors principals: Ricci, Vito, Peterson, Marnie L., Rotschafer, John C., Wexler, Hannah, Piddock, Laura J. V.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC375253/
https://ncbi.nlm.nih.gov/pubmed/15047539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.4.1344-1346.2004
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