Oxidative stress disrupts purinergic neuromuscular transmission in the inflamed colon

Colitis, induced by trinitrobenzene sulfonic acid (TNBS) in guinea pig, leads to decreased purinergic neuromuscular transmission resulting in a reduction in inhibitory junction potentials (IJPs) in colonic circular muscle. We explored possible mechanisms responsible for this inflammation-induced neu...

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Autori principali: Roberts, Jane A, Durnin, Leonie, Sharkey, Keith A, Mutafova-Yambolieva, Violeta N, Mawe, Gary M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2013
Soggetti:
Alimentary
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752453/
https://ncbi.nlm.nih.gov/pubmed/23732648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.254136
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