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Adenylyl cyclase 6 mediates the action of cyclic AMP-dependent secretagogues in mouse pancreatic exocrine cells via protein kinase A pathway activation

Both secretin and vasoactive intestinal polypeptide (VIP) receptors are responsible for the activation of adenylyl cyclases (ACs), which increase intracellular cyclic AMP (cAMP) levels in the exocrine pancreas. There are nine membrane-associated isoforms, each with its own pattern of expression and...

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Bibliografiske detaljer
Main Authors: Sabbatini, Maria E, D’Alecy, Louis, Lentz, Stephen I, Tang, Tong, Williams, John A
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752451/
https://ncbi.nlm.nih.gov/pubmed/23753526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.249698
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