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The Relevance of the TGF-β Paradox to EMT-MET Programs

The role of transforming growth factor-β (TGF-β) during tumorigenesis complex and paradoxical, reflecting its ability to function as a tumor suppressor in normal and early-stage cancers, and has a tumor promoter in their late-stage counterparts. The switch in TGF-β function is known as the “TGF-β Pa...

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Bibliografiske detaljer
Main Authors: Morrison, Chevaun D., Parvani, Jenny G., Schiemann, William P.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752409/
https://ncbi.nlm.nih.gov/pubmed/23474494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.02.048
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