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Progesterone receptor signaling in the microenvironment of endometrial cancer influences its response to hormonal therapy

Progesterone, an agonist for the progesterone receptor (PR), can be an efficacious and well-tolerated treatment in endometrial cancer. The clinical use of progesterone is limited due to the lack of biomarkers that predict hormone sensitivity. Despite its efficacy in cancer therapy, mechanisms and si...

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Detalhes bibliográficos
Main Authors: Janzen, D.M., Rosales, M.A., Paik, D.Y., Lee, D.S., Smith, D.A., Witte, O.N., Iruela-Arispe, M.L., Memarzadeh, S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752407/
https://ncbi.nlm.nih.gov/pubmed/23744837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-0930
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