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Insulin-Like Growth Factor-1 Abrogates Microglial Oxidative Stress and TNF-α Responses to Spreading Depression

Spreading depression (SD), the most likely cause of migraine aura and perhaps migraine, occurs with increased oxidative stress (OS). SD increases reactive oxygen species (ROS), and ROS, in turn, can signal to increase neuronal excitability, which includes increased SD susceptibility (SDS). SD also e...

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Detalhes bibliográficos
Main Authors: Grinberg, Yelena Y., Dibbern, Megan E., Levasseur, Victoria A., Kraig, Richard P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752330/
https://ncbi.nlm.nih.gov/pubmed/23586526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12267
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