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Generation of hair cells in neonatal mice by β-catenin overexpression in Lgr5-positive cochlear progenitors
Mammalian hair cells do not regenerate, and their loss is a major cause of deafness. We recently identified leucine-rich repeat containing, G-protein-coupled receptor 5 (Lgr5)-expressing cochlear supporting cells with the capacity for self-renewal and hair cell differentiation in vitro. We found tha...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3752268/ https://ncbi.nlm.nih.gov/pubmed/23918377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219952110 |
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