Investigating Models of Protein Function and Allostery With a Widespread Mutational Analysis of a Light-Activated Protein

To investigate the relationship between a protein’s sequence and its biophysical properties, we studied the effects of more than 100 mutations in Avena sativa light-oxygen-voltage domain 2, a model protein of the Per-Arnt-Sim family. The A. sativa light–oxygen–voltage domain 2 undergoes a photocycle...

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Autors principals: Zayner, Josiah P., Antoniou, Chloe, French, Alexander R., Hause, Ronald J., Sosnick, Tobin R.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2013
Matèries:
Proteins and Nucleic Acids
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752136/
https://ncbi.nlm.nih.gov/pubmed/23972854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.07.010
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