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Introducing Titratable Water to All-Atom Molecular Dynamics at Constant pH

Recent development of titratable coions has paved the way for realizing all-atom molecular dynamics at constant pH. To further improve physical realism, here we describe a technique in which proton titration of the solute is directly coupled to the interconversion between water and hydroxide or hydr...

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Detalhes bibliográficos
Main Authors: Chen, Wei, Wallace, Jason A., Yue, Zhi, Shen, Jana K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752133/
https://ncbi.nlm.nih.gov/pubmed/23972860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.06.036
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