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A Cross-Bridge Cycle with Two Tension-Generating Steps Simulates Skeletal Muscle Mechanics

We examined whether cross-bridge cycle models with one or two tension-generating steps can account for the force-velocity relation of and tension response to length steps of frog skeletal muscle. Transition-state theory defined the strain dependence of the rate constants. The filament stiffness was...

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Autori principali: Offer, Gerald, Ranatunga, K.W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752108/
https://ncbi.nlm.nih.gov/pubmed/23972845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.07.009
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