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Coupled Reversible and Irreversible Bistable Switches Underlying TGFβ-induced Epithelial to Mesenchymal Transition

Epithelial to mesenchymal transition (EMT) plays an important role in embryonic development, tissue regeneration, and cancer metastasis. Whereas several feedback loops have been shown to regulate EMT, it remains elusive how they coordinately modulate EMT response to TGF-β treatment. We construct a m...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tian, Xiao-Jun, Zhang, Hang, Xing, Jianhua
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752104/
https://ncbi.nlm.nih.gov/pubmed/23972859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.07.011
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