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Characterizing a Histidine Switch Controlling pH-Dependent Conformational Changes of the Influenza Virus Hemagglutinin

During the fusion of the influenza virus to the host cell, bending of the HA2 chain of hemagglutinin into a hairpin-shaped structure in a pH-dependent manner facilitates the fusion of the viral envelope and the endosomal membrane. To characterize the structural and dynamical responses of the hinge r...

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Main Authors: Kalani, Mohamad R., Moradi, Abdulvahab, Moradi, Mahmoud, Tajkhorshid, Emad
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752100/
https://ncbi.nlm.nih.gov/pubmed/23972851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.06.047
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