Rapid induction of intraneuronal neurofibrillary tangles in apolipoprotein E-deficient mice

Cultured hippocampal slices prepared from apolipoprotein E-deficient mice were exposed to an inhibitor of cathepsins B and L and then processed for immunocytochemistry using antibodies against human paired helical filaments. Dense, AT8-immunopositive deposits were found in the subiculum, stratum ori...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Bi, Xiaoning, Yong, Alex P., Zhou, Jun, Ribak, Charles E., Lynch, Gary
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 2001
Subjects:	Biological Sciences
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC37521/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11438710/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.151253098
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