LIS1 Deficiency Promotes Dysfunctional Synaptic Integration of Granule Cells Generated in the Developing and Adult Dentate Gyrus

Type I lissencephaly, a neuronal migration disorder characterized by cognitive disability and refractory epilepsy, is often caused by heterozygous mutations in the LIS1 gene. Histopathologies of malformation-associated epilepsies have been well described, but it remains unclear whether hyperexcitabi...

Full description

Saved in:
Bibliographic Details
Main Authors: Hunt, Robert F., Dinday, Matthew T., Hindle-Katel, William, Baraban, Scott C.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2012
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752080/
https://ncbi.nlm.nih.gov/pubmed/22973010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1286-12.2012
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items