Different Responses of Macrophages to Smooth and Rough Brucella spp.: Relationship to Virulence

By comparing smooth wild-type Brucella strains to their rough mutants, we show that the lipopolysaccharide (LPS) O side chain of pathogenic Brucella has a dramatic impact on macrophage activation. It favors the development of virulent Brucella by preventing the synthesis of immune mediators, importa...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Jiménez de Bagüés, María P., Terraza, Annie, Gross, Antoine, Dornand, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2004
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC375206/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15039375/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.4.2429-2433.2004
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