Combined Zoledronic Acid and Meloxicam Reduced Bone Loss and Tumor Growth in an Orthotopic Mouse Model of Bone-Invasive Oral Squamous Cell Carcinoma

Oral squamous cell carcinoma is common in cats and humans and invades oral bone. We hypothesized that the cyclooxygenase-2 inhibitor, meloxicam, with the bisphosphonate, zoledronic acid (ZOL), would inhibit tumor growth, osteolysis and invasion in feline oral squamous cell carcinoma (OSCC) xenograft...

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Hlavní autoři: Martin, C.K., Dirksen, W.P., Carlton, M.M., Lanigan, L.G., Pillai, S.P., Werbeck, J.L., Simmons, J.K., Hildreth, B.E., London, C.A., Toribio, R.E., Rosol, T.J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751980/
https://ncbi.nlm.nih.gov/pubmed/23651067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/vco.12037
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