Neutralization of Interleukin-10 Significantly Enhances Gamma Interferon Expression in Peripheral Blood by Stimulation with Johnin Purified Protein Derivative and by Infection with Mycobacterium avium subsp. paratuberculosis in Experimentally Infected Cattle with Paratuberculosis

Monoclonal antibody neutralization of interleukin-10 (IL-10) increased Johnin purified protein derivative-induced whole-blood gamma interferon (IFN-γ) secretion 23-fold and also increased IFN-γ secretion ninefold following in vitro Mycobacterium avium subsp. paratuberculosis infection of peripheral...

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Hlavní autoři: Buza, Joram J., Hikono, Hirokazu, Mori, Yasuyuki, Nagata, Reiko, Hirayama, Sachiyo, Bari, Abusaleh M., Shu, Yujing, Tsuji, Noriko M., Momotani, Eiichi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC375198/
https://ncbi.nlm.nih.gov/pubmed/15039374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.4.2425-2428.2004
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