Barrier Disrupting Effects of Alternaria Alternata Extract on Bronchial Epithelium from Asthmatic Donors

Sensitization and exposure to the allergenic fungus Alternaria alternata has been associated with increased risk of asthma and asthma exacerbations. The first cells to encounter inhaled allergens are epithelial cells at the airway mucosal surface. Epithelial barrier function has previously been repo...

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Main Authors: Leino, Marina S., Loxham, Matthew, Blume, Cornelia, Swindle, Emily J., Jayasekera, Nivenka P., Dennison, Patrick W., Shamji, Betty W. H., Edwards, Matthew J., Holgate, Stephen T., Howarth, Peter H., Davies, Donna E.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751915/
https://ncbi.nlm.nih.gov/pubmed/24009658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071278
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